South San Francisco lies north of San Bruno and San Francisco International Airport in a small valley south of Daly City, Colma, Brisbane, and San Bruno Mountain, east of Pacifica and the hills of the Coast Range, and west of the waters of San Francisco Bay. Locals often refer to the town as "South City," in much the same way that San Francisco is called "The City." Despite its name, the South San Francisco does not border San Francisco, with Brisbane being between them.